The Coalition for Health, Ethics and Society (CHES) aims to promote multi-stakeholder dialogue between health and non-health practitioners on topical health issues. CHES events and publications particular attention to the ethical aspects of health and issues regarding access to healthcare, affordability and patient choice. CHES is a joint initiative by the EPC and Johnson & Johnson. Its activities are governed by a Steering Committee and managed by the EPC. CHES is independent of all stakeholders. In 2020-2021, the overarching theme is ‘Investing in health and well-being – The cornerstone of an economy that works for people’. In this context, CHES activities will focus on how investment in people’s health and well-being can be a driver of social and economic progress and address the ongoing societal transformations, while also reflecting on the EU role in delivering on the promises of global sustainable development.