The Health and Societal Resilience Programme (HSR) focus is on society’s ability to recover from crises and economic shocks. In recent years, the European Union has come under increasing pressure as a result of permanent and overlapping crises, and the societal and political repercussions these have generated. The economic and social disparities among EU member states, coupled with rising nationalism and populism, all point to a need to focus on areas where citizens experience a loss of trust in governments – such as in housing or healthcare.

The European Politics and Institutions Programme covers the EU’s institutional architecture, governance and policymaking to ensure that it can move forward and respond to the challenges of the 21st century democratically and effectively. It also monitors and analyses political developments at the EU level and in the member states, discussing the key questions of how to involve European citizens in the discussions over the Union’s future and how to win their support for European integration. The Programme has a special focus on enlargement policy towards the Western Balkans, questions of EU institutional reform and illiberal trends in European democracies.

The European Migration and Diversity (EMD) Programme provides independent expertise on European migration and asylum policies. The EMD Programme's analyses seek to contribute to sustainable and responsible policy solutions and are aimed at promoting a positive and constructive dialogue on migration and mobility. The Programme follows the policy debate and conducts analysis taking a multidisciplinary approach, examining both the legal and political aspects shaping European migration policies. EMD analysts focus, amongst other topics, on the reform of the Common European Asylum System; the management of the EU’s external borders and the Schengen governance; cooperation with countries of origin and transit; the integration of beneficiaries of international protection and mobile persons into host societies; the links between migration and populism; the development of resettlement and legal pathways; and the EU''s free movement acquis. The EMD team benefits from a strong network of academics, NGO representatives and policymakers, who contribute regularly to publications and policy events.

The EPC’s Europe’s Political Economy Programme (EPE) focuses on EU economic governance, the single market, and digital, industrial, energy, trade, and economic security policies amid significant geo-economic and technological shifts. In a world of rising geopolitical competition and a fragmenting economy, the EPE has been at the forefront of research on Europe’s competitiveness agenda, the "triple" green, digital and economic security transitions and "wartime economy". The EPE's cross-programme flagship initiative, the Brussels Economic Security Forum, examines EU-US-China dynamics, changing international economic rules and statecraft, as well as related EU policy challenges. As fast-advancing components of economic security, critical emerging technologies in clean tech, semiconductor and AI value chains and quantum are priority areas of focus. Using its convening power and multistakeholder taskforce model, the Programme aims to provide in-depth analysis and actionable recommendations to tackle key policy challenges. The EPE team comprises a diverse group of analysts with backgrounds from government, the private sector, academia, and journalism, bringing a broad range of expertise to its work.

The Sustainable Prosperity for Europe (SPfE) Programme explores the foundations and drivers for achieving a sustainable, resilient and competitive European economy. Prospering within the planetary boundaries requires rethinking our economic model, including our production and consumption patterns, as well as our energy, mobility and food systems. It requires addressing the climate emergency and environmental degradation, as well as becoming smarter with the resources we have. The transition to the world we want must bring both businesses and people along, if it is to succeed. The Paris Agreement and the Sustainable Development Agenda provide the direction for travel globally and in Europe, and the SPfE Programme engages in a debate on the drivers and the means for achieving our goals. The Programme focuses on areas where working together across the EU can bring significant benefits to the member states, citizens and businesses and can ensure sustainable prosperity within the limits of this planet.

The Europe in the World (EiW) Programme scrutinises the impact of a changing international system on Europe and probes how the EU and its member states can advance their interests and values on a regional and global level. It examines the EU’s relations with both major and middle powers around the world, and how Europe can continue to contribute to a rules-based global order. Secondly, the Programme focuses on the role of the EU in fostering reform, resilience and stability in neighbouring regions and looks closely at developments in Turkey and Ukraine, among other countries. Thirdly, the Programme examines and seeks to advance the development of Europe’s security and defence policy.

The Transnationalisation Programme (TN) facilitates a transnationalised debate on Europe’s key challenges through enhancing collaboration with think tanks and civil society across Europe. Today’s global and societal challenges require transnational policy responses. European think tanks and civil society play an important role in connecting debates across borders and strengthening exchanges between decision-makers and other relevant stakeholders.